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Janne Lehtiö Selected Research

Hyperplasia

1/2020PCSK6 Is a Key Protease in the Control of Smooth Muscle Cell Function in Vascular Remodeling.
1/2016Phenotypic Modulation of Smooth Muscle Cells in Atherosclerosis Is Associated With Downregulation of LMOD1, SYNPO2, PDLIM7, PLN, and SYNM.

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Janne Lehtiö Research Topics

Disease

40Neoplasms (Cancer)
01/2022 - 09/2007
7Breast Neoplasms (Breast Cancer)
11/2021 - 01/2011
5Inflammation (Inflammations)
01/2020 - 10/2015
5Carcinoma (Carcinomatosis)
01/2020 - 10/2010
5Alzheimer Disease (Alzheimer's Disease)
01/2019 - 12/2012
5Lung Neoplasms (Lung Cancer)
09/2012 - 12/2007
4Neoplasm Metastasis (Metastasis)
01/2020 - 01/2011
3Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
01/2022 - 03/2015
3Neuroblastoma
01/2018 - 06/2013
3Adenoma (Adenomas)
01/2018 - 10/2010
3Papillary Thyroid Cancer
01/2015 - 10/2010
3Adenocarcinoma of Lung
03/2014 - 07/2009
2Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2021 - 06/2008
2Atherosclerotic Plaque (Atheroma)
01/2020 - 08/2018
2Hyperplasia
01/2020 - 01/2016
2Melanoma (Melanoma, Malignant)
01/2020 - 01/2017
2Thyroid Neoplasms (Thyroid Cancer)
04/2016 - 04/2012
2Pleural Effusion (Pleural Effusions)
03/2014 - 07/2009
2Papillary Carcinoma
04/2012 - 10/2010
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
05/2011 - 01/2011
1Hypoxia (Hypoxemia)
11/2021
1Triple Negative Breast Neoplasms
07/2021
1Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker)
12/2020
1Type 2 Diabetes Mellitus (MODY)
08/2020
1Vascular Remodeling
01/2020
1Cutaneous Malignant Melanoma
01/2020
1Kyphosis
12/2019
1Alopecia (Baldness)
12/2019
1Premature Aging
12/2019
1Chronic Obstructive Pulmonary Disease (COPD)
11/2019
1Pneumonia (Pneumonitis)
11/2019
1Amyloid Plaque
01/2019
1Noninfiltrating Intraductal Carcinoma (DCIS)
01/2019
1Glioma (Gliomas)
01/2019
1Glioblastoma (Glioblastoma Multiforme)
01/2019
1Herpes Simplex
01/2019
1Antiphospholipid Syndrome (Antiphospholipid Antibody Syndrome)
01/2019
1Carotid Artery Diseases
08/2018

Drug/Important Bio-Agent (IBA)

31Proteins (Proteins, Gene)FDA Link
01/2022 - 12/2007
15Biomarkers (Surrogate Marker)IBA
01/2020 - 09/2007
12ProteomeIBA
01/2022 - 07/2008
8Pharmaceutical PreparationsIBA
01/2022 - 09/2010
7Peptides (Polypeptides)IBA
01/2022 - 08/2008
5Biological ProductsIBA
01/2019 - 07/2008
4EnzymesIBA
11/2021 - 01/2011
3Neoplasm Antigens (Tumor Antigens)IBA
01/2022 - 07/2021
3Messenger RNA (mRNA)IBA
01/2021 - 09/2013
3TamoxifenFDA LinkGeneric
01/2015 - 01/2011
2AntigensIBA
01/2022 - 07/2021
2VaccinesIBA
10/2021 - 07/2021
2RNA (Ribonucleic Acid)IBA
01/2021 - 03/2015
2Phosphotransferases (Kinase)IBA
01/2020 - 05/2013
2Peptide Hydrolases (Proteases)FDA Link
01/2020 - 01/2018
2Blood Proteins (Serum Proteins)IBA
01/2020 - 02/2010
2Amyloid (Amyloid Fibrils)IBA
01/2019 - 01/2018
2CalciumIBA
01/2018 - 01/2015
2Estrogens (Estrogen)FDA Link
01/2018 - 01/2015
2AllergensIBA
01/2018 - 01/2013
2MicroRNAs (MicroRNA)IBA
10/2015 - 12/2013
1Cancer VaccinesIBA
01/2022
1Cystine (L-Cystine)IBA
11/2021
1SulfurIBA
11/2021
1Cysteine (L-Cysteine)FDA Link
11/2021
1Sulfides (Thioethers)IBA
11/2021
1LyasesIBA
11/2021
1Ligases (Synthetase)IBA
11/2021
1LigandsIBA
10/2021
1DystrophinIBA
12/2020
1PalmitatesIBA
08/2020
1Nonesterified Fatty Acids (NEFA)IBA
08/2020
1adavosertibIBA
01/2020
1Immune Checkpoint InhibitorsIBA
01/2020
1MTOR InhibitorsIBA
01/2020
1Cytarabine (Cytosar-U)FDA LinkGeneric
01/2020
1DeoxycytidineIBA
01/2020
1DNA (Deoxyribonucleic Acid)IBA
01/2020
1KynurenineIBA
01/2020
1MitogensIBA
01/2020
1Platelet-Derived Growth FactorIBA
01/2020
1Proto-Oncogene Proteins c-sis (Platelet Derived Growth Factor B)IBA
01/2020
1Matrix Metalloproteinases (MMPs)IBA
01/2020
1Mitogen-Activated Protein KinasesIBA
01/2020
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
01/2020
1Metalloproteases (Metalloproteinases)IBA
01/2020
1Mitochondrial DNA (mtDNA)IBA
12/2019
1Anti-Bacterial Agents (Antibiotics)IBA
11/2019
1Lupus Coagulation Inhibitor (Lupus Anticoagulant)IBA
01/2019
1Triglycerides (Triacylglycerol)IBA
01/2019
1AntibodiesIBA
01/2019
1Phenobarbital (Luminal)FDA Link
01/2019
1Protein CoronaIBA
01/2019
1Fibrinogen (Factor I)FDA Link
01/2019
1Syndecan-1 (Syndecan 1)IBA
01/2019

Therapy/Procedure

7Therapeutics
01/2020 - 12/2007
3Immunotherapy
01/2022 - 01/2018
2Lasers (Laser)
10/2010 - 11/2009
1Molecular Targeted Therapy
11/2021
1Drug Therapy (Chemotherapy)
01/2020
1Ligation
01/2020
1Carotid Endarterectomy
08/2018